Oral microbiome in systemic disease

The oral microbiome is established within a few minutes after birth and consists of stable multi‐species communities that engage in a dynamic equilibrium with the host immune system. Dental caries, endodontic infections and periodontal diseases are bacterially driven diseases that are caused by dysbiotic microbiomes.

Periodontal Disease Bacteria May...

Long-term exposure to periodontal disease bacteria causes inflammation and degeneration of brain neurons in mice that is similar to the effects of Alzheimer’s disease in humans, according to a new study from researchers at the University of Illinois at Chicago.

Subversion to systemic inflammation

Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health. Recent studies have provided insights into the emergence and persistence of dysbiotic oral microbial communities, which can mediate inflammatory pathology at local as well as distant sites.

Cancer and Dental Health

More than one-third of all cancer patients develop complications that affect the mouth, according to the National Institute of Dental and Craniofacial Research. These mild to severe side effects can include mouth sores, infection, dry mouth, sensitive gums and jaw pain.